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Reduced Order Modelling for parametric Electrical Impedance Tomography

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ROMpEIT

Welcome to the ROMpEIT Toolbox

The framework for Reduced Order Modelling for parametric Electrical Impedance Tomography.

Copyright 2024, Matthew R. Walker and Leandro Beltrachini

Description

This git repo contains the toolbox for the ROMpEIT framework. Reduced Order Modelling is a numerical technique for the rapid calculation of paramterised boundary value problems. Parametric Electrical Impedance Tomography is a technique to estimate the conductivites of the tissues in the head, containing within it many boundary value problems to solve. This toolbox marries the two techniques for rapid solutions to the pEIT problem.

To use this work please cite as appropriate (citation to be updated soon)

Installation and Setup

Firstly, download this git repository:

git clone https://github.com/09nwalkerm/ROMpEIT.git

Next, make a directory in which you would like to keep the results generated by the toolbox. Then navigate to the setup/ directoy in ROMpEIT and source the set_env.sh script to set some environment variables. When prompted, add the path to the results folder you made. Then type "y" when asked to create a log folder.

mkdir ROMpEIT_results
cd ROMpEIT/setup/
. set_env.sh

You're now ready to start matlab and use the toolbox or submit SLURM jobs. Please see the example.m script for an idea of the general workflow.

BLEIGIFP installation

It is highly recommended that you install the BLEIGIFP matlab code for solving generalised eigenvalue problems. The code can be downloaded here. Make sure to add this function to your MATLAB path.

Documentation

The documentation for each function and class in this toolbox can be found here.

Getting Started

In this section we aim to provide a basic walk-through of a typical use case for the software. This is one possible pipeline for the software but it gives an overview of the main functions and their inputs in this toolbox. Prerequisites: MATLAB R2021A or later with the Statistics and Machine Learning Toolbox.

Please see the example.m script in the scripts/ folder for the full tutorial. Before running the example script or beginning this tutorial, please make sure the environment is set up correctly by sourcing the setup/set_env.sh script (see Installation and Setup above). If you have installed the BLEIGIFP script, please make sure it is added to your MATLAB path.

In this example, we have a spherical head model represented by a finite element mesh with 84k nodes and 485k tetrahedrons. It is important that this mesh has the nodes labelled as 'p', the tetrahrdons labelled as 't' and also the surface triangular mesh labelled as 'f'. For 't', the fifth column must contain the tissue number that the element belongs to. For 'f', the fourth column must contain the electrode number that the triangle belongs to. This is essential for any head model. This tutorial is designed to be lightweight so it can run on a single PC, therefore we only train for handlful of electrode pairs and bound interpolation points.

We start by defining the conductivity ranges that form our parameter space used to train ROM. Notice the min and max values of some tissues are the same. This tells ROM we don't want to train for those layers. Then we define the path to our model.

mu_min=[0.303,0.002,1.7,0.3,5]; % minimum conductivities
mu_max=[0.444,0.043,1.7,0.3,5]; % maximum conductivities

tree = getenv("ROMEG");

model = [tree '/models/Spherical/head_model.mat'];

Next, we create and save a file called sinks.mat that describes the injection and extraction electrodes used to train ROM. This creates only 3 patterns for training where the injections are electrodes 63, 64 and 65. All the sinks are set to the final electrode (120 in this case).

OrderedModelClass.patterns('model',model,'electrodes',[63,64,65])

The following function then generates the Reduced Order Model by training within the min and max conductivity ranges. The 'nic' value is the number of bound interpolation points and Nmax is the number of snapshots. The current is the total current injected. The same amount is then extracted from the sink electrode. We'll set debug to true so that we can check the logs if something goes wrong.

GenRBModel('model',model,'mu_min',mu_min,'mu_max',mu_max,'nic',10,...
    'Nmax',10,'current',0.02e-3,'debug',true)

We don't have any real EIT data for this model so we're going to make some noisey synthetic measurements to use in the inverse problem. This uses the model to simulate the behaviour of the current and then adds noise to the measurements to simulate real world use. In the function we define the noise we would like in Volts and the 'ground truth' conductivities that we later try to reconstruct in the inverse problem.

GenMeasurements('model',model,'noise',0.82e-6,'synth_cond',...
    [0.4,0.009,1.7,0.3,5],'debug',true)

Finally, we can run the Inverse Problem for ROMpEIT. We have to tell the function to use the same electrode patterns used in training with 'use_sinks' and also for it to read the noisey measurements with 'use_noise'. We can also specify the tissues we wish to estimate by using the 'active_layers' parameter. We select the first 2 tissues given that is what we trained ROM for. The argument 'ROM',true is also given to say we want to use the reduced order model for the inverse problem. To use the traditional method of pEIT, use 'TRAD',true instead. Lastly, we need to add a ground electrode. We chose 1 here, although any electrode that isn't used in an injection pair would do.

GenInverse('model',model,'ROM',true,'current',0.02e-3,...
    'use_sinks',true,'use_noise',true,'debug',true,...
    'active_layers',[1 2],'ground',1)

Notice how it runs almost instantly AND the estimated values are really close to the synthetic values. You are encouraged to play around with the parameters, especially the conductivities.

Try adding the 'simultaneous',true pair to the GenInverse function to see all the electrode pairs be estimated together in one optimisation.

This tutorial only gives a breif guide, and there are many more features and configurations to explore. To get started with them, either see the documentation, or type 'help' with any function into the MATLAB command line for the full list of arguments.

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