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Update the histological description of the dorsal vessel #1337

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merged 13 commits into from
Dec 9, 2021

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@gouttegd gouttegd commented Dec 8, 2021

This PR uses recent anatomical and histological studies (notably Lehmacher et al., 2012 [FBrf0219200]) to give more precise descriptions of the cell types that make up the dorsal vessel in both the larva and the adult.

closes #1289
closes #17

Update the definition of 'cardial cell' to remove the notion of
contractility, since the term is used to refer to all cells that form
the wall of the dorsal vessel, including the cells that form the ostia
and the intracardial valves.

Add an adult-specific 'adult cardial cell' term, on par with the
existing 'embryonic/larval cardial cell'.

Add cell numbers as provided by Lehmacher et al. (2012) [FBrf0219200].
Add 'contractile cardiommyocyte' as a subclass of 'cardiomyocyte' to
refer to the largest fraction of cardiomyocytes, those whose function is
to propel the hemolymph through the dorsal vessel.

Re-classify the existing 'adult heart circular muscle cell' and 'larval
heart circular muscle cell' as subclasses of 'contractile
cardiomyocyte'.
Add 'ostial cell' as a subclass of 'cardial cell', along with
stage-specific subclasses.
Add 'intracardial valve cell' as a subclass of 'cardial cell', along
with stage-specific subclasses.
Update the definition for the larval heart to remove the mention of 3
chambers (not found in recent descriptions).

Update the definition of 'adult ostium' to mention that there are 5
pairs of ostium in the adult heart, not 4 (the first chamber contains 2
pairs).

Update 'ostiolar valve' to indicate that the cells making up these
structures are the newly added 'ostial cells'.
Add a new term to represent the intracardial valves formed by the
intracardial valve cells.
Provide a bit more detail about the arrangement of cardiomyocytes in the
dorsal vessel.
@gouttegd gouttegd requested a review from Clare72 December 8, 2021 13:23
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gouttegd commented Dec 8, 2021

We should also probably merge embryonic dorsal vessel (FBbt:00005680, no definition, used in 71 records) with embryonic/larval dorsal vessel (FBbt:0001673, with a complete definition, used in 554 records).

However I am unsure about what to do with the EmbDevSlim subset annotation carried by embryonic dorsal vessel but not by embryonic/larval dorsal vessel. What is this annotation for, and if we merge the two terms, can we simply move the annotation to the “surviving” term?

@gouttegd gouttegd requested a review from Clare72 December 8, 2021 17:21
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Clare72 commented Dec 9, 2021

I would not do this merge as part of this PR as it will probably require a bit of extra research (and informing the curators), which can be done as part of #1138

Rephrase so that the definition does not exclude anything not listed.
Also remove the association with a longitudinal layer.

Re-classify 'adult contractile cardiomyocyte' as an 'adult circular
muscle cell' under that new definition.
Make sure ostiolar valves are 'part of' the dorsal vessel and that
ostial cells are 'part of' ostiolar valves.
The correct adjective for 'ostium' is 'ostial'. 'Ostiolar' is the
adjective for 'ostiole', which is a different term that seems more used
for plants than for animals.
@gouttegd gouttegd merged commit f9bf051 into master Dec 9, 2021
@gouttegd gouttegd deleted the update-cardial-cell branch December 9, 2021 11:57
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"cardial cell" vs "adult heart muscle cell" Add ultrastructural detail for larval heart cells [sf#17]
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