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Update README.md
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Updated as per the scSNViz on 10/23/24
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tushar2016sharma authored Oct 25, 2024
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-d, --disable-ind-plots
Disable individual SNV plots. Default=F.

-v, --display-ind-plots
Display individual scSNV plots in the combined HTML. Default=F.
-v, --hide-ind-plots
Hide individual scSNV plots in the combined HTML. Default=F.

-e, --disable-3d-axis
Disable axes in 3D plots. Default=F.
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├── Histogram_TotalVAF.png
└── Individual_sceSNVs/
├── VARreads/
│ └── 3D VARreads plot HTML files for each sceSNV
│ └── 3D N_VAR plot HTML files for each sceSNV
├── REFreads/
│ └── 3D REFreads plot HTML files for each sceSNV
│ └── 3D N_REF plot HTML files for each sceSNV
└── VAF/
└── 3D VAF plot HTML files for each sceSNV
```
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**Individual_sceSNVs**: contains 3D dmensionality reduction plots for _individual sceSNV_ of the following:
- Expressed Variant Allele Fraction per cell (VAF_RNA)
- Number of Reference Reads per cell (REFreads)
- Number of Variant Reads per cell (VARreads)
- Number of Reference Reads per cell (N_REF)
- Number of Variant Reads per cell (N_VAR)

**Exploratory_Combined_Plots**: displays all the separately generated plots above into one single html for modularity

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## Installation

Download the R file:
- [scSNViz.r](https://raw.githubusercontent.com/HorvathLab/NGS/master/scSNViz/scSNViz.r) (Updated: 10/01/2024)
- [scSNViz.r](https://raw.githubusercontent.com/HorvathLab/NGS/master/scSNViz/scSNViz.r) (Updated: 10/23/2024)

The following CRAN packages are required:
- optparse, stringr, openxlsx, HGNChelper, Seurat, ggplot2, dplyr, plotly, htmlwidgets, htmltools, jsonlite.
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