CeL-ID is a new method developed for cell line authentication using variant profiles derived from RNA-seq data. Benchmarking studies on independent test sets have shown its robustness. CeL-ID successfully identifies identical, synonymous and derivative cell lines and also estimates about the possible contaminant. We have attempted to provide simple solution to problem associated with cell line authentication and hope this would help in adoption of regular cell line authentication.
Data Files: Due to size limitations we have only uploaded COSMIC70 matched data files here. Complete variants data files can be downloaded from following links:
CCLE_FREQ.txt: https://uthscsa.box.com/s/53xzna3mdv8mrxt6w9838glqe9vvrxvu
CCLE_DP.txt: https://uthscsa.box.com/s/cq029cq307iaxttjnv5k3z0yaq5gdrwx
CCLE_DP.txt - It shows depth of coverage (DP) values for all the variants derived from CCLE RNA-seq dataset.
CCLE_FREQ.txt - It shows allele frequency (FREQ) values for all the variants derived from CCLE RNA-seq dataset.
Query_DP.txt - It shows depth of coverage (DP) values for the variants discovered in MCF7 cells (data from GSE86316)
Query_FREQ.txt - It shows allele frequency (FREQ) values for the variants discovered in MCF7 cells (data from GSE86316)
COSMIC70_matched files - Complete list of COSMIC 70 matched variants with DP and FREQ values, respectively (compressed format).
If you have any questions, please contact us at [email protected] OR [email protected].