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unable to access index for repository https://cran.rstudio.com/bin/macosx/big-sur-arm64/contrib/4.5:

unable to access index for repository https://cran.rstudio.com/bin/macosx/big-sur-arm64/contrib/4.5:

harfbuzz 10.0.1_1 is already installed and up-to-date. To reinstall 10.0.1_1, run: brew reinstall harfbuzz

fribidi 1.0.16 is already installed and up-to-date. To reinstall 1.0.16, run: brew reinstall fribidi

macOS's Gatekeeper has been disabled for this Cask

dependencies ‘BiocVersion’, ‘BiocStyle’ are not available

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