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Added VDJ concatenation modules and added MuData object #435

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Added VDJ concatenation module to concatenate "filtered_contig_annotation" files from scirpy package.
Added MuData module to create MuData objects to handle VDJ, and CITE-seq modalities. Specifically MuData object is built only for filtered count matrices (not raw) from GEX and CITE-seq modalities.

  • This comment contains a description of changes (with reason).
  • If you've fixed a bug or added code that should be tested, add tests!
  • If you've added a new tool - have you followed the pipeline conventions in the contribution docs
  • If necessary, also make a PR on the nf-core/scrnaseq branch on the nf-core/test-datasets repository.
  • Make sure your code lints (nf-core pipelines lint).
  • Ensure the test suite passes (nextflow run . -profile test,docker --outdir <OUTDIR>).
  • Check for unexpected warnings in debug mode (nextflow run . -profile debug,test,docker --outdir <OUTDIR>).
  • Usage Documentation in docs/usage.md is updated.
  • Output Documentation in docs/output.md is updated.
  • CHANGELOG.md is updated.
  • README.md is updated (including new tool citations and authors/contributors).

@saraterzo saraterzo marked this pull request as draft February 27, 2025 14:44
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3 participants