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ViralConsensus v0.0.2

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@niemasd niemasd released this 12 Jul 19:55
· 60 commits to master since this release
  • Fixed bug when handling minority insertions with sufficiently high coverage (thanks @alexcritschristoph!)
    • Normally, if an erroneous insertion is encountered, the number of reads supporting that insertion should be low
    • However, if sequencing is deep enough, the number of reads supporting that insertion could exceed the "minimum coverage" threshold, even though there could be a ton of reads that don't have that insertion
      • E.g. if there are 100 reads with ACGT and 1,000,000 reads with ACT (no G), the ACGT would still appear in the consensus
    • To patch this, we now correctly count "no insertion" between matches/mismatches