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SNP23: Analyzing the genomic differences between wild type strains (as published in reference genomes) and strains kept under lab conditions (resequenced by the Segrè lab in 2019)

❓Questions we are trying to answer:

  • What are the SNPs in the re-sequenced genomes (vs original genomes? I.e., how many SNAPs/genome, location of SNPs, what genes are affected?
  • What are other genomic changes compared with the original genome? E.g, rearrangements, paralogs.
  • Is there conservancy in the number of SNPs based on phylogenetic relationships? I.e Do closely-related microbes undergo similar changes?

🔗 Useful Links:

Shared Notes on Google Drive: https://drive.google.com/drive/folders/1ZNowof5NB3n_OAjHu4QRoAtlrP9T6WHK?usp=drive_link

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Variant Calling on Marine Strains (2023)

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