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tcga-vcf-reheader-tool

Tool to read a TCGA Variant Call Format (VCF) file and output an equivalent file with a different header

Requirements

  • Python 2.7
  • PyYAML

Usage

tcga-vcf-reheader.py input_file_path output_file_path parameter_file_path
  • input_file_path: the VCF to read
  • output_file_path: the VCF to write
  • parameter_file_path: a YAML file describing the additions/changes to the header

Currently only changes to the ##SAMPLE lines are supported. Any existing ##SAMPLE lines will be replaced by the ones specified in the YAML file.

WARNING: This tool will completely replace any existing ##SAMPLE lines. If the parameter file names different samples than were used in the VCF, the resulting output will be a misleading chimeric monster.

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tcgavcf-tool

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