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This project truly deserves a clean, well organized and good looking repository.
I moved source code files to a "src" directory and modified the Makefiles to write the binaries into a "bin" directory (a standard used by most projects). A ".gitignore" was added in order to prevent binary files being staged on commits.
The README file was also lacking more useful information, so I wrote one based on the previous file and the cd-hit web page.