COVID-19 ACE2 Variants - Published Paper Version

COVID-19 ACE2 Variants - Official Release

Release v1.0 - Published Paper Version

This release marks the official version of the "COVID-19 ACE2 Variants" repository as referenced in our published paper. The code and data in this release have been used to generate the analysis and figures presented in our research on the impact of ACE2 variants on SARS-CoV-2 infection.

Published Work Reference:

MacGowan SA, Barton MI, Kutuzov M, Dushek O, van der Merwe PA, et al. (2022). "Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants." PLOS Computational Biology 18(3): e1009922. Link to Publication

Zenodo DOI:

This release is also archived on Zenodo: https://www.doi.org/10.5281/zenodo.10523095

Acknowledgements:

We thank all contributors and collaborators who have been part of this project. Your invaluable input has been instrumental in the success of this research.

For any queries or further information, please contact Stuart MacGowan at [email protected].

How to Cite:

If you use the data or code from this release in your research, please cite our published paper and the Zenodo DOI.

Note:

This official release is being created some years after the original publication of our research paper. While the repository has been publicly available on GitHub, this formal release is intended to clearly mark the specific version of the code and data that were used in our published study. It corresponds to the version of the code used at that time, with some minor improvements made to the repository's README document only.