DomainAnalysis

Domain-Level Analyses in AltAnalyze

AltAnalyze allows users to identify putative protein domains, motifs or microRNA bindings potentially disrupted by alternative splicing in their experiment. These results are incredibly useful at prioritizing results in terms of functional effects (e.g. modified DNA-binding domains).

These results are returned in the form of spreadsheets that indicate affected domains and associated protein isoforms for each analyzed splicing-event. The following links provide additional details on these analyses.

• Example analyses
• Overview of associated file types
• Description of the algorithm and underlying annotations.
• Detailed examples results
• Visualization in DomainGraph