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Can Alkan edited this page Jul 22, 2018 · 19 revisions

mrFAST: micro-read Fast Alignment Search Tool.

mrFAST is designed to map short reads generated with the Illumina platform to reference genome assemblies; in a fast and memory-efficient manner.

Currently supported features:

  • Output in SAM format
  • Indels up to 8 bp (4 bp deletions and 4 bp insertions)
  • Paired-end mapping
    • Discordant option to generate mapping file ready for VariationHunter to detect structural variants.
  • One end anchored (OEA) map locations for novel sequence insertion detection with NovelSeq
  • Matepair library mapping (long inserts with RF orientation).

Implemented, not-yet-released features:

  • Multithreading